A global health problem caused by arsenic from natural sources

被引：585
作者：
Ng, JC [1 ]
Wang, JP [1 ]
Shraim, A [1 ]
机构：
[1] Univ Queensland, Natl Res Ctr Environm Toxicol, Brisbane, Qld 4108, Australia
来源：
CHEMOSPHERE | 2003年 / 52卷 / 09期
关键词：
arsenic; coal; speciation; environmental health; arsenicosis; arsenism; carcinogen; cancer;
D O I：
10.1016/S0045-6535(03)00470-3
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
Arsenic is a carcinogen to both humans and animals. Arsenicals have been associated with cancers of the skin, lung, and bladder. Clinical manifestations of chronic arsenic poisoning include non-cancer end point of hyper- and hypo-pigmentation, keratosis, hypertension, cardiovascular diseases and diabetes. Epidemiological evidence indicates that arsenic concentration exceeding 50 mug l(-1) in the drinking water is not public health protective. The current WHO recommended guideline value for arsenic in drinking water is 10 mug l(-1), whereas many developing countries are still having a value of 50 mug 1(-1). It has been estimated that tens of millions of people are. at risk exposing to excessive levels of arsenic from both contaminated water and arsenic-bearing coal from natural sources. The global health implication and possible intervention strategies were also discussed in this review article. (C) 2003 Elsevier Ltd. All rights reserved.
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收藏
页码：1353 / 1359
页数：7
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