Latex allergy in pediatric emergency department personnel

Allergy to natural latex proteins has been recently recognized as a dangerous entity among health care professionals. Cutaneous symptoms related to latex glove use vary from the redness and scaling of contact dermatitis to urticaria, In addition, anaphylactic reactions have been reported. We report the spectrum of reactions to latex glove use in 93 members of our emergency department (ED) staff during a one-month study period, In addition, we attempt to correlate these symptoms with serologic evidence of atopy and latex allergy, Eighty-four of these subjects underwent total serum immunoglobulin E and latex-specific radioallergosorbent test (RAST) testing, Fifty-four percent of subjects reported symptoms relating to latex glove use, categorized as either contact dermatitis (48.4%) or urticaria (5.4%), Of the urticaria group, two subjects reported additional symptoms related to latex glove use such as rhinitis, conjunctivitis, or sneezing, All three groups of subjects (asymptomatic, contact dermatitis, and urticaria) were alike with respect to age, sex, and race, The urticaria group reported a higher incidence of environmental allergies (chi(2), P = 0.02). Serum total immunoglobulin E levels and latex-specific RAST results did not differ among the three groups, The one subject with a positive latex-specific RAST reported urticarial and nasoocular symptoms when exposed to latex gloves, Seventeen percent of symptomatic subjects reported decreased use of latex gloves because of these symptoms, It was concluded that many members of our pediatric ED staff exhibit a sensitivity to latex antigens, Clinical symptoms, rather than serologic testing, must be used to identify latex-sensitive individuals in this setting, Recommendations are offered to assist In the identification and management of hospital personnel who exhibit allergy to latex-containing products.