A Case of Concurrent Leukocytosis and Systemic Capillary Leak Syndrome Due to Pegfilgrastim

被引：2

作者：

Gotera, Nico ^{[1
]}

Hasan, Shayee ^{[1
]}

Shrestha, Pritee ^{[1
]}

Heleno, Caio ^{[1
]}

Tesar, Amy ^{[1
]}

机构：

[1] MercyOne North Iowa Med Ctr, Internal Med, Mason City, IA 50401 USA

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2022年 / 14卷 / 05期

关键词：

neulasta; leukocytosis; pegfilgrastim; neupogen; filgrastim; granulocyte colony-stimulating factor; systemic capillary leak syndrome;

D O I：

10.7759/cureus.24640

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Pegfilgrastim is a granulocyte colony-stimulating factor agent used in patients receiving myelosuppressive therapy with chemotherapy or radiation. Two adverse effects associated with this agent include capillary leak syndrome and leukocytosis. To our knowledge, this is the first case of a patient who developed both systemic capillary leak syndrome and leukocytosis greater than 100,000 cells/mu L after receiving pegfilgrastim. This patient received early fluid resuscitation, vasopressor support, and methylprednisolone, which improved her clinical course during hospitalization.

引用

页数：5

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