A Unique Case of Merkel Cell Carcinoma with Ovarian Metastasis

被引：4

作者：

Acikalin, Arbil ^{[1
]}

Paydas, Semra ^{[2
]}

Gulec, Umran Kucukgoz ^{[3
]}

Uguz, Aysun ^{[1
]}

Gumurdulu, Derya ^{[1
]}

机构：

[1] Cukurova Univ, Fac Med, Dept Pathol, Adana, Turkey

[2] Cukurova Univ, Fac Med, Dept Med Oncol, Adana, Turkey

[3] Cukurova Univ, Fac Med, Dept Gynecol & Obstet, Adana, Turkey

来源：

BALKAN MEDICAL JOURNAL | 2014年 / 31卷 / 04期

关键词：

Carcinoma; Merkel cell; metastasis ovarian; neoplasms;

D O I：

10.5152/balkanmedj.2014.14117

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: Merkel cell carcinoma (MCC) is a rare cutaneous/mucosal malignancy with very aggressive biology and increasing incidence. Ovarian metastasis is an exceptionally rare site for MCC, and only two cases have been reported in the literature. Case Report: We report MCC with ovarian metastasis. A 34 year-old female with previously excised MCC from preauricular skin presented with a pelvic mass 15 months after first diagnosis. Anti-cytokeratin (CK) 20 positivity, LCA (leucocyte common antigen), and TTF-1 (Thyroid transcription factor-1) negativity confirmed metastatic ovarian MCC. There was no evidence of recurrence or metastasis at 12 months after salpingo-oopherectomy. Conclusion: MCC should be considered in the differential diagnosis of primary and metastatic undifferentiated small round cell tumors of the ovary.

引用

页码：356 / 359

页数：4

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