VRmol: an integrative web-based virtual reality system to explore macromolecular structure

被引：14
作者：
Xu, Kui [1 ,2 ,3 ]
Liu, Nan [2 ,3 ,4 ]
Xu, Jingle [1 ,2 ]
Guo, Chunlong [3 ]
Zhao, Lingyun [2 ,4 ]
Wang, Hong-Wei [2 ,3 ,4 ]
Zhang, Qiangfeng Cliff [1 ,2 ,3 ]
机构：
[1] Tsinghua Univ, MOE Key Lab Bioinformat, Sch Life Sci, Beijing 100084, Peoples R China
[2] Tsinghua Univ, Beijing Frotier Res Ctr Biol Struct, Beijing Adv Innovat Ctr Struct Biol, Beijing 100084, Peoples R China
[3] Tsinghua Univ, Tsinghua Peking Joint Ctr Life Sci, Beijing 100084, Peoples R China
[4] Tsinghua Univ, Sch Life Sci, Key Lab Prot Sci, Minist Educ, Beijing 100084, Peoples R China
来源：
BIOINFORMATICS | 2021年 / 37卷 / 07期
基金：
中国国家自然科学基金;
关键词：
D O I：
10.1093/bioinformatics/btaa696
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
A Summary: Structural visualization and analysis are fundamental to explore macromolecular functions. Here, we present a novel integrative web-based virtual reality (VR) system-VRmol, to visualize and study molecular structures in an immersive virtual environment. Importantly, it is integrated with multiple online databases and is able to couple structure studies with associated genomic variations and drug information in a visual interface by cloud-based drug docking. VRmol thus can serve as an integrative platform to aid structure-based translational research and drug design.
引用
收藏
页码：1029 / 1031
页数：3
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