Transmission of Helicobacter pylori infection in families of preschool-aged children from Minas Gerais, Brazil

被引：45
作者：
Rocha, GA
Rocha, AMC
Silva, LD
Santos, A
Bocewicz, ACD
Queiroz, RD
Bethony, J
Gazzinelli, A
Corrêa-Oliveira, R
Queiroz, DMM
机构：
[1] Univ Fed Minas Gerais, Fac Med, Lab Res Bacteriol, BR-30130100 Belo Horizonte, MG, Brazil
[2] Ctr Pesquisas Rene Rachou Fiocruz, FIOCRUZ, Lab Imunol Celular & Mol, BR-30190002 Belo Horizonte, MG, Brazil
[3] Univ Fed Minas Gerais, Escola Enfermagem, BR-30130100 Belo Horizonte, MG, Brazil
[4] George Washington Univ, Med Ctr, Dept Microbiol & Trop Med, Washington, DC 20037 USA
来源：
TROPICAL MEDICINE & INTERNATIONAL HEALTH | 2003年 / 8卷 / 11期
关键词：
Helicobacter pylori; transmission; epidemiology;
D O I：
10.1046/j.1360-2276.2003.01121.x
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
We evaluated the role of the family in the transmission of Helicobacter pylori infection in preschool-aged children from a rural district in the State of Minas Gerais, Brazil. Sixty-six families (66 index children, 63 mothers, 60 fathers and 134 siblings), defined as at least one parent living in the same household with at least one offspring up to 8 years old, were studied. Odds ratios (OR) and 95% confidence intervals (CI) were estimated by logistic regression controlling for age, gender, number of children in household and H. pylori status of the father, mother and siblings. The prevalence of the infection was 69.7% (469 of 673) and it increased with age (P < 0.001). Positive mothers were a strong and independent risk factor for infection (OR 22.70; 95% CI 2.31-223.21). Positive siblings were also positively associated with infection (OR 1.81; 95% CI 1.01-3.30).
引用
收藏
页码：987 / 991
页数：5
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