Hyaluronan-binding properties of human serum hemopexin

被引：25
作者：
Hrkal, Z
Kuzelova, K
MullerEberhard, U
Stern, R
机构：
[1] CORNELL UNIV, COLL MED, DEPT PEDIAT HEMATOL ONCOL, NEW YORK, NY 10021 USA
[2] UNIV CALIF SAN FRANCISCO, SCH MED, DEPT PATHOL, SAN FRANCISCO, CA 94143 USA
来源：
FEBS LETTERS | 1996年 / 383卷 / 1-2期
关键词：
hemopexin; hyaluronic acid; affinity electrophoresis;
D O I：
10.1016/0014-5793(96)00225-6
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Hemopexin, the heme-binding serum glycoprotein, exhibits a complex electrophoretic pattern on two-dimensional immunoelectrophoresis on agarose gels into which hyaluronic acid is incorporated in the first and monospecific anti-hemopexin in the second dimension. This heterogeneity reflects a range of interactions of hemopexin isoforms with hyaluronic acid. Electrophoretic patterns of individual human sera greatly differ in their contents of hyaluronan-interacting hemopexin species. Hemopexin itself has no hyaluronidase activity.
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收藏
页码：72 / 74
页数：3
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