Cervical cancer: Prevention, diagnosis, and therapeutics

被引：121

作者：

Janicek, MF ^{[1
]}

Averette, HE

机构：

[1] OncoGyne PC, Phoenix, AZ USA

[2] Univ Miami, Sch Med, Miami, FL 33101 USA

来源：

CA-A CANCER JOURNAL FOR CLINICIANS | 2001年 / 51卷 / 02期

关键词：

D O I：

10.3322/canjclin.51.2.92

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Cervical cancer is a leading cause of cancer deaths in women worldwide. Because of its association with human papilloma virus infection, as well as the ability to screen for premalignant stages of the disease, it is now largely a preventable disease. This article describes the molecular basis for cervical cancer, and presents a clinical overview of current treatment approaches and technological advances, emphasizing the unique aspects of this viral disease as it relates to the immune system and vaccination or other immunotherapeutic strategies.

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页码：92 / 114

页数：23

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共 128 条

[91]

Ressing ME, 1996, CANCER RES, V56, P582

[92] Determinants of squamous intraepithelial lesions (SIL) on Pap smear: The role of HPV infection and of HIV-1-induced immunosuppression [J].

Rezza G. ;

Giuliani M. ;

Branca M. ;

Benedetto A. ;

Migliore G. ;

Garbuglia A.R. ;

D'Ubaldo C. ;

Pezzotti P. ;

Cappiello G. ;

Pomponi Formiconi D. ;

Suligoi B. ;

Schiesari A. ;

Ippolito G. ;

Giacomini G. ;

Sinicco A. ;

Volante R. ;

Errante I. ;

Cecchini G.C. ;

Quirino T. ;

Agarossi A. ;

Bergamasco A. ;

Lomini M. ;

Vaccher E. ;

Sopracordevole F. ;

Visonà R. ;

Leveni R. ;

Sighinolfi L. ;

Segala V. ;

Boschini A. ;

Gentili G. ;

Pozzi M. ;

Carvelli C. ;

Lirosi G. ;

Montella F. ;

Soraci R. ;

Liuzzi G. ;

Sansone M. ;

Gargiulo M. ;

Congedo P. ;

Carriero C. .

European Journal of Epidemiology, 1997, 13 (8) :937-943

[93]

Ries LA., 2000, SEER CANC STAT REV 1

[94] THE ASCUS SWAMP [J].

ROBB, JA .

DIAGNOSTIC CYTOPATHOLOGY, 1994, 11 (04) :319-320

[95] Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer [J].

Rose, PG ;

Bundy, BN ;

Watkins, EB ;

Thigpen, JT ;

Deppe, G ;

Maiman, MA ;

Clarke-Pearson, DL ;

Insalaco, S .

NEW ENGLAND JOURNAL OF MEDICINE, 1999, 340 (15) :1144-1153

[96] Positron emission tomography for evaluating para-aortic nodal metastasis in locally advanced cervical cancer before surgical staging: A surgicopathologic study [J].

Rose, PG ;

Adler, LP ;

Rodriguez, M ;

Faulhaber, PF ;

Abdul-Karim, FW ;

Miraldi, F .

JOURNAL OF CLINICAL ONCOLOGY, 1999, 17 (01) :41-45

[97] Paclitaxel and cisplatin as first-line therapy in recurrent or advanced squamous cell carcinoma of the cervix: A Gynecologic Oncology Group study [J].

Rose, PG ;

Blessing, JA ;

Gershenson, DM ;

McGehee, R .

JOURNAL OF CLINICAL ONCOLOGY, 1999, 17 (09) :2676-2680

[98] Oral vaccination of mice with human papillomavirus virus-like particles induces systemic virus-neutralizing antibodies [J].

Rose, RC ;

Lane, C ;

Wilson, S ;

Suzich, JA ;

Rybicki, E ;

Williamson, AL .

VACCINE, 1999, 17 (17) :2129-2135

[99] PARA-AORTIC NODAL METASTASES IN EARLY CERVICAL-CARCINOMA - LONG-TERM SURVIVAL FOLLOWING EXTENDED-FIELD RADIOTHERAPY [J].

RUBIN, SC ;

BROOKLAND, R ;

MIKUTA, JJ ;

MANGAN, C ;

SUTTON, G ;

DANOFF, B .

GYNECOLOGIC ONCOLOGY, 1984, 18 (02) :213-217

[100] THE HPV-16 E6 AND E6-AP COMPLEX FUNCTIONS AS A UBIQUITIN-PROTEIN LIGASE IN THE UBIQUITINATION OF P53 [J].

SCHEFFNER, M ;

HUIBREGTSE, JM ;

VIERSTRA, RD ;

HOWLEY, PM .

CELL, 1993, 75 (03) :495-505

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