An advanced case of gastric histiocytic sarcoma treated with chemotherapy and gastrectomy: a case report and review of literature

被引:4
作者
Matsunaga, Ryu [1 ]
Kanazawa, Yoshikazu [1 ]
Matsuno, Kunihiko [1 ]
Kakinuma, Daisuke [1 ]
Tokura, Taichiro [2 ]
Marumo, Atsushi [2 ]
Yui, Shunsuke [2 ]
Ando, Fumihiko [1 ]
Masuda, Yuka [1 ]
Hagiwara, Nobutoshi [1 ]
Nomura, Tsutomu [1 ]
Kato, Shunji [1 ]
Yoshiyuki, Toshiro [1 ]
Domoto, Yukako [3 ]
Sakatani, Takashi [3 ]
Ohashi, Ryuji [3 ,4 ]
Inokuchi, Koiti [2 ]
Yoshida, Hiroshi [1 ]
机构
[1] Nippon Med Sch, Dept Gastrointestinal & Hepatobiliary Pancreat Su, Bunkyo Ku, 1-1-5 Sendagi, Tokyo 1138603, Japan
[2] Nippon Med Coll Hosp, Dept Hematol, Bunkyo Ku, 1-1-5 Sendagi, Tokyo 1138603, Japan
[3] Nippon Med Coll Hosp, Dept Diagnost Pathol, Bunkyo Ku, 1-1-5 Sendagi, Tokyo 1138603, Japan
[4] Nippon Med Sch, Dept Integrated Diagnost Pathol, Bunkyo Ku, 1-1-5 Sendagi, Tokyo 1138603, Japan
关键词
Histiocytic sarcoma; Stomach; Gastrectomy; COMBINATION; ETOPOSIDE; DIAGNOSIS; LYMPHOMA; CHOP;
D O I
10.1007/s12328-021-01438-y
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Histiocytic sarcoma is a relatively new disease category and the gastrointestinal origin is sporadic. We report a case of a 74-year-old woman who underwent chemotherapy and proximal gastrectomy for extremely rare, advanced gastric histiocytic sarcoma. The resected specimen was subjected to numerous immunostainings to meet the diagnostic criteria of histiocytic sarcoma and was positive for the histiocyte markers' cluster of differentiation 68 and lysozyme. The markers of Langerhans cells, follicular dendritic cells, and myelocyte were all negative. Six reports of surgical resection of histiocytic sarcoma originating in the stomach exist, including our case. We reviewed the clinical course and the histological and immunohistochemical diagnostic features of surgically resected gastric histiocytic sarcoma.
引用
收藏
页码:1053 / 1059
页数:7
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