The state of the immune system in thyroidectomized rats

被引：4
|
作者：
Bendyug, GD [1 ]
Grinevich, YA [1 ]
Khranovskaya, NN [1 ]
Fil'chakov, FV [1 ]
Yugrinova, LG [1 ]
Kad'kalenko, AG [1 ]
机构：
[1] Ukraine Acad Med Sci, Inst Oncol, UA-252655 Kiev, Ukraine
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2003年 / 135卷 / 02期
关键词：
thyroid; immune system; hypothyrosis; rats;
D O I：
10.1023/A:1023819914926
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Disorders in the immune system manifesting in decreased weight and cellularity of lymphoid organs, decreased count of large granular lymphocytes, suppression of the immune response and metabolic activity of macrophages were observed in experimental animals 1-6 months after thyroidectomy. The intensity of these disorders depends on the period elapsed after the surgery. These disorders can result from not only changes in the levels of the pituitary-thyroid hormones, but also disturbances in the endocrine function of the thymus in thyroidectomized animals.
引用
收藏
页码：154 / 157
页数：4
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