Adjuvant Therapy for Stage I and II Non-Small Cell Lung Cancer

被引：11

作者：

Naylor, Evan C. ^{[1
]}

机构：

[1] Meridian Canc Care, Southern Ocean Med Ctr, Hematol & Oncol, 1140 Route 72 West, Manahawkin, NJ 08050 USA

来源：

SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA | 2016年 / 25卷 / 03期

关键词：

Adjuvant; Chemotherapy; Non-small cell lung cancer; RESPIRATORY SOCIETY CLASSIFICATION; VINORELBINE PLUS CISPLATIN; PREOPERATIVE CHEMOTHERAPY; INTERNATIONAL-ASSOCIATION; POOLED ANALYSIS; PHASE-III; INDEPENDENT PREDICTOR; COMPARING CISPLATIN; RECURRENCE SCORE; TUMOR RECURRENCE;

D O I：

10.1016/j.soc.2016.03.003

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Patients with stage I and stage II non-small cell lung cancer undergoing complete resection have a 40% to 70% 5-year overall survival despite optimal local therapy. Chemotherapy administered after complete resection has been shown to improve overall survival at 5 years by approximately 5%. This improvement in survival may be confined to patients with stage IB disease 4 cm or greater, and to those with hilar or mediastinal lymph node involvement. The optimal chemotherapy regimen appears to be cisplatin-based doublet or triplet chemotherapy for 3 to 4 cycles. The addition of biologic agents has failed to improve outcomes.

引用

页码：585 / +

页数：17

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