Opinion -: Is mood chemistry?

被引：435
作者：
Castrén, E [1 ]
机构：
[1] Univ Helsinki, Ctr Neurosci, FIN-00014 Helsinki, Finland
来源：
NATURE REVIEWS NEUROSCIENCE | 2005年 / 6卷 / 03期
基金：
芬兰科学院;
关键词：
D O I：
10.1038/nrn1629
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The chemical hypothesis of depression suggests that mood disorders are caused by a chemical imbalance in the brain, which can be corrected by antidepressant drugs. However, recent evidence indicates that problems in information processing within neural networks, rather than changes in chemical balance, might underlie depression, and that antidepressant drugs induce plastic changes in neuronal connectivity, which gradually lead to improvements in neuronal information processing and recovery of mood.
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收藏
页码：241 / 246
页数：6
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