C-H Activation/Functionalization Catalyzed by Simple, Well-Defined Low-Valent Cobalt Complexes

被引：96

作者：

Fallon, Brendan J. ^{[1
]}

Derat, Etienne ^{[1
]}

Amatore, Muriel ^{[1
]}

Aubert, Corinne ^{[1
]}

Chemla, Fabrice ^{[1
]}

Ferreira, Franck ^{[1
]}

Perez-Luna, Alejandro ^{[1
]}

Petit, Marc ^{[1
]}

机构：

[1] Univ Paris 06, Sorbonne Univ, CNRS, Inst Parisien Chim Mol,UMR 8232, F-75252 Paris 05, France

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2015年 / 137卷 / 07期

关键词：

BOND ACTIVATION; REGIOSELECTIVE CYCLOMETALATION; CARBON-HYDROGEN; AROMATIC IMINES; ALKYNES; HYDROARYLATION; ARYL; IRON; FUNCTIONALIZATION; CLEAVAGE;

D O I：

10.1021/ja512728f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A facile C-H activation and functionalization of aromatic imines is presented using low-valent cobalt catalysts. Using Co(PMe3)(4) as catalyst we have developed an efficient and simple protocol for the C-H/hydroarylation of alkynes with an anti selectivity. Deuterium-labeling experiments, DFT calculations coupled with the use of a well-defined catalyst have for the first time shed light on the elusive black box of cobalt catalyzed C-H functionalization.

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收藏

页码：2448 / 2451

页数：4

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