Noninvasive monitoring of blood glucose concentration in diabetic patients with optical coherence tomography

被引：35

作者：

Lan, Y. T. ^{[1
]}

Kuang, Y. P. ^{[1
]}

Zhou, L. P. ^{[2
,3
]}

Wu, G. Y. ^{[4
]}

Gu, P. C. ^{[2
,3
]}

Wei, H. J. ^{[2
,3
]}

Chen, K. ^{[1
]}

机构：

[1] Guangdong Pharmaceut Univ, Guangzhou 510310, Guangdong, Peoples R China

[2] South China Normal Univ, MOE Key Lab Laser Life Sci, Guangzhou 510631, Guangdong, Peoples R China

[3] South China Normal Univ, Coll Biophoton, Inst Laser Life Sci, Guangzhou 510631, Guangdong, Peoples R China

[4] Sun Yat Sen Univ, Affiliated Hosp 1, Dept Surg, Guangzhou 510080, Guangdong, Peoples R China

来源：

LASER PHYSICS LETTERS | 2017年 / 14卷 / 03期

基金：

高等学校博士学科点专项科研基金; 中国国家自然科学基金;

关键词：

optical coherence tomography; OCT signal slope; correlation coefficient; diabetic patients; blood glucose concentration;

D O I：

10.1088/1612-202X/aa58c0

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Optical coherence tomography (OCT) has been used to noninvasively monitor the blood glucose concentration (BGC) in healthy subjects with good accuracy and acceptable specificity. Based on this, the paper further considered the possibility of OCT in noninvasive monitoring BGC in diabetic patients. The OCT signal slope (OCTSS) changed with variation of BGC. The correlation coefficient R between BGC and OCTSS in diabetic patients was 0.91; while the correlation coefficient R in healthy volunteers was 0.78. Thus, a better linear dependence of OCTSS on BGC in diabetic patients was presented in the experiment. The results showed that the capability and accuracy of OCT in noninvasive monitoring BGC of diabetic patients, and the noninvasive monitoring BGC in diabetic patients may be better than the monitoring in the healthy subjects.

引用

页数：6

共 38 条

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