Synthesis and NMR characterization of monomethoxypoly(ethylene glycol) aldehydes from monomethoxypoly(ethylene glycol) tosylates

被引：3

作者：

Ladd, DL ^{[1
]}

Henrichs, PM ^{[1
]}

机构：

[1] Nycomed Amersham Imaging, Wayne, PA USA

来源：

SYNTHETIC COMMUNICATIONS | 1998年 / 28卷 / 22期

关键词：

D O I：

10.1080/00397919809458693

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A procedure for the synthesis of monomethoxypoly(ethylene glycol) aldehydes from monomethoxypoly(ethylene glycol) tosylates is described. The tosylates are converted to aldehydes in high yield via treatment with disodium hydrogen phosphate and DMSO; minimal oligomeric by-products are formed.

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页码：4143 / 4149

页数：7

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