Correlation between serum level of, and tissue positivity for, alpha-fetoprotein in hepatocellular carcinoma

被引：0

作者：

Ogawa, A ^{[1
]}

Kanda, T ^{[1
]}

Sugihara, S ^{[1
]}

Kobayashi, I ^{[1
]}

Nakazato, Y ^{[1
]}

机构：

[1] GUNMA CANC CTR, DEPT PATHOL, OTA, GUMMA 373, JAPAN

来源：

JOURNAL OF MEDICINE | 1996年 / 27卷 / 1-2期

关键词：

alpha-fetoprotein; hepatocellular carcinoma; serum levels;

D O I：

暂无

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The serum level of alpha-fetoprotein (AFP) is a marker for primary liver tumors. To evaluate the relationship between the serum level of AFP and the positivity of liver tissue for this marker, specimens of liver were obtained at autopsy from patients with hepatocellular carcinoma(HCC). Tissues were fixed with formalin or Kryofix and immunostained for AFP. Serum AFP titer at autopsy was positively correlated with AFP staining in tissue fixed by Kryofix and stained with monoclonal antibody against AFP. The correlation was significant for plasma levels of AFP above 5,000 ng/ml. Results suggest that elevated serum AFP levels are an indicator of the progression of HCC.

引用

页码：33 / 40

页数：8

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