Argonautes team up to silence transposable elements in Arabidopsis

被引：3

作者：

Underwood, Charles J. ^{[1
]}

Martienssen, Robert A. ^{[1
]}

机构：

[1] Gordon & Betty Moore Fdn, Watson Sch Biol Sci, Howard Hughes Med Inst, Cold Spring Harbor Lab, Cold Spring Harbor, NY 11724 USA

来源：

EMBO JOURNAL | 2015年 / 34卷 / 05期

基金：

美国国家科学基金会;

关键词：

SIRNA ACCUMULATION; DNA METHYLATION; MECHANISM; AGO6;

D O I：

10.15252/embj.201590971

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The de novo silencing of transposable elements in plants and animals is mediated in part by RNA-directed chromatin modification. In flowering plants, AGO4 has been seen as the key argonaute protein in the RNA-directed DNA methylation pathway that links the plant-specific RNA polymerase V with the de novo DNA methyltransferase DRM2 (Zhong et al, 2014). Two recent papers in The EMBO Journal strongly implicate a role for the AGO6 protein in the process of de novo silencing.

引用

页码：579 / 580

页数：2

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