Recommendations for transfusion of blood products in neonatology

被引:0
作者
Boix, Hector [1 ]
Dolores Sanchez-Redondo, Maria [2 ]
Cernada, Maria [3 ,4 ]
Espinosa Fernandez, Maria Gracia [5 ]
Gonzalez-Pacheco, Noelia [6 ]
Martin, Ana [7 ]
Perez-Munuzuri, Alejandro [8 ,9 ]
Couce, Maria L. [8 ,9 ]
机构
[1] Hosp Quironsalud, Serv Terr Pediat, Barcelona, Spain
[2] Hosp Virgen Salud, Unidad Neonatol, Toledo, Spain
[3] Hosp Univ & Politecn La Fe, Serv Neonatol, Valenvia, Spain
[4] Inst Invest Sanitaria La Fe, Grp Invest Perinatol, Valenvia, Spain
[5] Hosp Reg Univ Malaga, Unidad Neonatol, Malaga, Spain
[6] Hosp Gen Univ Gregorio Maranon, Serv Neonatol, Madrid, Spain
[7] Hosp St Joan Deu, Serv Neonatol, Barcelona, Spain
[8] Hosp Clin Univ Santiago, Serv Neonatol, Santiago De Compostela, A Coruna, Spain
[9] Univ Santiago de Compostela, Inst Invest Sanitarias Santiago IDIS, Santiago De Compostela, A Coruna, Spain
来源
ANALES DE PEDIATRIA | 2022年 / 97卷 / 01期
关键词
Red blood cells; Platelets; Plasma; Premature; Newborn; Transfusion; BIRTH-WEIGHT INFANTS; CELL TRANSFUSION; THRESHOLDS; GUIDELINES; ANEMIA; MANAGEMENT; TRIAL; NEED;
D O I
10.1016/j.anpedi.2022.05.004
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
The scant evidence on the use of transfusions in neonatal care explains the limitations of current clinical guidelines. Despite this, in this document we explore the most recent evidence to make recommendations for the clinical practice. The prevention of anaemia of prematurity, the use of protocols and restrictive transfusion strategies constitute the best approach for clinicians in this field. In the case of platelet transfusions, the risk of bleeding must be assessed, combining clinical and laboratory features. Lastly, fresh frozen plasma is recommended in neonates with coagulopathy and active bleeding, with congenital factor deficiencies for which there is no specific treatment or with disseminated intravascular coagulation. All blood products have adverse effects that warrant a personalised and thorough assessment of the need for transfusion. (C) 2022 Asociacion Espanola de Pediatria. Published by Elsevier Espana, S.L.U.
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页数:8
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