Class in antiarrhythmic drugs block a cloned human inward rectifier potassium channel by interacting with the putative transmembrane segment M2.

被引：0
|
作者：
Kiehn, J [1 ]
Wible, B [1 ]
Ficker, E [1 ]
Taglialatela, M [1 ]
Brown, AM [1 ]
机构：
[1] CASE WESTERN RESERVE UNIV, RAMMELKAMP CTR RES, CLEVELAND, OH 44106 USA
来源：
BIOPHYSICAL JOURNAL | 1996年 / 70卷 / 02期
关键词：
D O I：
暂无
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
引用
收藏
页码：TU271 / TU271
页数：1
相关论文
共 19 条
  • [1] CLONED HUMAN INWARD RECTIFIER POTASSIUM CHANNEL AS A TARGET FOR CLASS-III ANTIARRHYTHMIC DRUGS
    KIEHN, J
    WIBLE, B
    FICKER, E
    TAGLIALATELA, M
    BROWN, AM
    CIRCULATION, 1995, 92 (08) : 758 - 758
  • [2] Mapping the block of a cloned human inward rectifier potassium channel by dofetilide
    Kiehn, J
    Wible, B
    Lacerda, AE
    Brown, AM
    MOLECULAR PHARMACOLOGY, 1996, 50 (02) : 380 - 387
  • [3] Scanning mutagenesis of the putative transmembrane segments of K(ir)2.1, an inward rectifier potassium channel
    Collins, A
    Chuang, HH
    Jan, YN
    Jan, LY
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (10) : 5456 - 5460
  • [4] BLOCK OF A CLONED HUMAN CARDIAC DELAYED RECTIFIER BY CLASS-III ANTIARRHYTHMIC AGENTS
    SNYDERS, D
    KNOTH, K
    ROBERDS, S
    BENNETT, PB
    TAMKUN, M
    FASEB JOURNAL, 1992, 6 (01): : A151 - A151
  • [5] CLONED HUMAN INWARD RECTIFIER K+ CHANNEL AS A TARGET FOR CLASS-III METHANESULFONANILIDES
    KIEHN, J
    WIBLE, B
    FICKER, E
    TAGLIALATELA, M
    BROWN, AM
    CIRCULATION RESEARCH, 1995, 77 (06) : 1151 - 1155
  • [6] Class III antiarrhythmic drugs block HERG, a human cardiac delayed rectifier K+ channel - Open-channel block by methanesulfonanilides
    Spector, PS
    Curran, ME
    Keating, MT
    Sanguinetti, MC
    CIRCULATION RESEARCH, 1996, 78 (03) : 499 - 503
  • [7] DIFFERENTIAL BLOCK OF CARDIAC DELAYED RECTIFIER CURRENT BY CLASS IC ANTIARRHYTHMIC DRUGS - EVIDENCE FOR OPEN CHANNEL BLOCK AND UNBLOCK
    FOLLMER, CH
    CULLINAN, CA
    COLATSKY, TJ
    CARDIOVASCULAR RESEARCH, 1992, 26 (11) : 1121 - 1130
  • [8] A NEW CLASS-III ANTIARRHYTHMIC DRUG, MS-551, BLOCKS THE INWARD RECTIFIER POTASSIUM CHANNEL IN ISOLATED GUINEA-PIG VENTRICULAR MYOCYTES
    SATO, R
    KOUMI, SI
    HISATOME, I
    TAKAI, H
    AIDA, Y
    OYAIZU, M
    KARASAKI, S
    MASHIBA, H
    KATORI, R
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 1995, 274 (01): : 469 - 474
  • [9] Effects of Ca2+-activated potassium and inward rectifier potassium channel on the differentiation of endothelial progenitor cells from human peripheral blood
    Gongjie Ye
    Haiwang Guan
    Justin Karush
    Feng Wang
    Xiaoyong Xu
    Haiyan Mao
    Xiaoyan Huang
    Xi Yang
    Ping Peng
    Yanna Ba
    Jianqing Zhou
    Jiangfang Lian
    Molecular Biology Reports, 2014, 41 : 3413 - 3423
  • [10] Effects of Ca2+-activated potassium and inward rectifier potassium channel on the differentiation of endothelial progenitor cells from human peripheral blood
    Ye, Gongjie
    Guan, Haiwang
    Karush, Justin
    Wang, Feng
    Xu, Xiaoyong
    Mao, Haiyan
    Huang, Xiaoyan
    Yang, Xi
    Peng, Ping
    Ba, Yanna
    Zhou, Jianqing
    Lian, Jiangfang
    MOLECULAR BIOLOGY REPORTS, 2014, 41 (05) : 3413 - 3423
12