共 33 条
Broadband superluminescent diode-based ultrahigh resolution optical coherence tomography for ophthalmic imaging
被引:37
作者:
Zhu, Dexi
[2
]
Shen, Meixiao
Jiang, Hong
Li, Ming
[2
]
Wang, Michael R.
[3
]
Wang, Yuhong
[2
]
Ge, Lili
[2
]
Qu, Jia
[2
]
Wang, Jianhua
[1
]
机构:
[1] Univ Miami, Miller Sch Med, Bascom Palmer Eye Inst, Dept Ophthalmol, Miami, FL 33136 USA
[2] Wenzhou Med Coll, Sch Ophthalmol & Optometry, Wenzhou 325000, Zhejiang, Peoples R China
[3] Univ Miami, Dept Elect & Comp Engn, Miami, FL 33136 USA
关键词:
optical coherence tomography;
ophthalmic imaging;
HIGH-SPEED;
DOMAIN;
OCT;
D O I:
10.1117/1.3660314
中图分类号:
Q5 [生物化学];
学科分类号:
071010 ;
081704 ;
摘要:
Spectral domain optical coherence tomography (SD-OCT) with ultrahigh resolution can be used to measure precise structures in the context of ophthalmic imaging. We designed an ultrahigh resolution SD-OCT system based on broadband superluminescent diode (SLD) as the light source. An axial resolution of 2.2 mu m in tissue, a scan depth of 1.48 mm, and a high sensitivity of 93 dB were achieved by the spectrometer designed. The ultrahigh-resolution SD-OCT system was employed to image the human cornea and retina with a cross-section image of 2048 x 2048 pixels. Our research demonstrated that ultrahigh -resolution SD-OCT can be achieved using broadband SLD in a simple way. (C) 2011 Society of Photo-Optical Instrumentation Engineers (SPIE). [DOI: 10.1117/1.3660314]
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