Broadband superluminescent diode-based ultrahigh resolution optical coherence tomography for ophthalmic imaging

被引：37

作者：

Zhu, Dexi ^{[2
]}

Shen, Meixiao

Jiang, Hong

Li, Ming ^{[2
]}

Wang, Michael R. ^{[3
]}

Wang, Yuhong ^{[2
]}

Ge, Lili ^{[2
]}

Qu, Jia ^{[2
]}

Wang, Jianhua ^{[1
]}

机构：

[1] Univ Miami, Miller Sch Med, Bascom Palmer Eye Inst, Dept Ophthalmol, Miami, FL 33136 USA

[2] Wenzhou Med Coll, Sch Ophthalmol & Optometry, Wenzhou 325000, Zhejiang, Peoples R China

[3] Univ Miami, Dept Elect & Comp Engn, Miami, FL 33136 USA

来源：

JOURNAL OF BIOMEDICAL OPTICS | 2011年 / 16卷 / 12期

关键词：

optical coherence tomography; ophthalmic imaging; HIGH-SPEED; DOMAIN; OCT;

D O I：

10.1117/1.3660314

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Spectral domain optical coherence tomography (SD-OCT) with ultrahigh resolution can be used to measure precise structures in the context of ophthalmic imaging. We designed an ultrahigh resolution SD-OCT system based on broadband superluminescent diode (SLD) as the light source. An axial resolution of 2.2 mu m in tissue, a scan depth of 1.48 mm, and a high sensitivity of 93 dB were achieved by the spectrometer designed. The ultrahigh-resolution SD-OCT system was employed to image the human cornea and retina with a cross-section image of 2048 x 2048 pixels. Our research demonstrated that ultrahigh -resolution SD-OCT can be achieved using broadband SLD in a simple way. (C) 2011 Society of Photo-Optical Instrumentation Engineers (SPIE). [DOI: 10.1117/1.3660314]

引用

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