Structures of amamistatins A and B, novel growth inhibitors of human tumor cell lines from an actinomycete

被引：38

作者：

Suenaga, K

Kokubo, S

Shinohara, C

Tsuji, T

Uemura, D ^{[1
]}

机构：

[1] Nagoya Univ, Grad Sch Sci, Dept Chem, Chikusa Ku, Nagoya, Aichi 4648602, Japan

[2] Sagami Chem Res Ctr, Sagamihara, Kanagawa 2290012, Japan

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 10期

关键词：

peptides; oxazoles; degradation; stereochemistry;

D O I：

10.1016/S0040-4039(99)00050-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two new lipopeptides, amamistatins A (1) and B, were isolated from an actinomycete. The absolute stereostructure of 1 was determined by spectroscopic and chemical analyses. Amamistatins A (1) and B showed growth inhibition for human tumor cell lines. (C) 1999 Elsevier Science Ltd. All rghts reserved.

引用

页码：1945 / 1948

页数：4

共 5 条

[1] Formobactin, a novel free radical scavenging and neuronal cell protecting substance from Nocardia sp [J].