A possible mechanism determining the stability of spiculated red blood cells

被引:74
|
作者
Iglic, A
机构
[1] Faculty of Electrical Engineering, University of Ljubljana, 1000 Ljubljana
关键词
cell shape; echinocyte; shear elasticity; bending energy; membrane skeleton;
D O I
10.1016/S0021-9290(96)00100-5
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
In this work the stability of spiculated red blood cells, caned echinocytes, is studied. It is assumed that the stable echinocyte shape corresponds to the minimum of its membrane elastic energy. It is shown that if the membrane skeleton shear elasticity is not taken into account the calculated stable echinocyte shapes always have only one spicule. However, by considering the skeleton shear elastic energy also, the calculated stable echinocyte shapes have many spicula in agreement with experimental observations. Copyright (C) 1996 Elsevier Science Ltd.
引用
收藏
页码:35 / 40
页数:6
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