Intravitreal triamcinolone acetonide in patients with macular oedema due to branch retinal vein occlusion:: a pilot study

被引:35
作者
Krepler, K [1 ]
Ergun, E [1 ]
Sacu, S [1 ]
Richter-Müksch, S [1 ]
Wagner, J [1 ]
Stur, M [1 ]
Wedrich, A [1 ]
机构
[1] Med Univ Vienna, Dept Ophthalmol, A-1090 Vienna, Austria
来源
ACTA OPHTHALMOLOGICA SCANDINAVICA | 2005年 / 83卷 / 05期
关键词
macular oedema; branch retinal vein occlusion; triamcinolone; intravitreal; NONINFECTIOUS ENDOPHTHALMITIS; INJECTION;
D O I
10.1111/j.1600-0420.2005.00490.x
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: To evaluate treatment of macular oedema due to branch retinal vein occlusion (BRVO) with intravitreal triamcinolone acetonide. Methods: In a prospective case series, nine patients with macular oedema due to BRVO received an intravitreal injection of 4 mg triamcinolone acetonide. Examination included best-corrected visual acuity (BCVA) for distance and reading, intraocular pressure (IOP) measurement, fluorescein angiography and high resolution imaging by optical coherence tomography, preoperatively and at 1 week, 1 month, 3 and 6 months postoperatively. Results: Preoperative mean BCVAs were 1.3 +/- 0.8 for distance vision, and 1.1 +/- 0.3 for reading acuity, respectively. A significant improvement in reading acuity was observed until 1 month (0.7 +/- 0.4, p = 0.02). No significant reduction in mean macular thickness was observed. Conclusions: Intravitreal injection of triamcinolone acetonide led to a significant improvement in mean VA in patients with macular oedema due to BRVO. However, the significant effect was not permanent and persisted for only 1 month.
引用
收藏
页码:600 / 604
页数:5
相关论文
共 28 条
[1]  
[Anonymous], 1984, AM J OPHTHALMOL, V98, P271
[2]   Exudative macular degeneration and intravitreal triamcinolone: 18 month follow up [J].
Challa, JK ;
Gillies, MC ;
Penfold, PL ;
Gyory, JF ;
Hunyor, ABL ;
Billson, FA .
AUSTRALIAN AND NEW ZEALAND JOURNAL OF OPHTHALMOLOGY, 1998, 26 (04) :277-281
[3]   Intravitreal triamcinolone acetonide for ischaemic macular oedema caused by branch retinal vein occlusion [J].
Chen, SDM ;
Lochhead, J ;
Patel, CK ;
Frith, P .
BRITISH JOURNAL OF OPHTHALMOLOGY, 2004, 88 (01) :154-155
[4]  
CLEMETT RS, 1973, T OPHTHAL SOC UK, V93, P523
[5]  
Danis RP, 2000, RETINA-J RET VIT DIS, V20, P244, DOI 10.1097/00006982-200003000-00004
[6]   Morphological and functional changes after intravitreal triamcinolone acetonide for retinal vein occlusion [J].
Degenring, RF ;
Kamppeter, B ;
Kreissig, I ;
Jonas, JB .
ACTA OPHTHALMOLOGICA SCANDINAVICA, 2003, 81 (04) :399-401
[7]   ISCHEMIC MACULAR EDEMA - RECOGNITION AND FAVORABLE NATURAL-HISTORY IN BRANCH VEIN OCCLUSION [J].
FINKELSTEIN, D .
ARCHIVES OF OPHTHALMOLOGY, 1992, 110 (10) :1427-1434
[8]   Intravitreal triamcinolone acetonide for macular oedema due to central retinal vein occlusion [J].
Greenberg, PB ;
Martidis, A ;
Rogers, AH ;
Duker, JS ;
Reichel, E .
BRITISH JOURNAL OF OPHTHALMOLOGY, 2002, 86 (02) :247-248
[9]   MACULAR EDEMA AND RETINAL BRANCH VEIN OCCLUSION [J].
GREER, DV ;
CONSTABLE, IJ ;
COOPER, RL .
AUSTRALIAN JOURNAL OF OPHTHALMOLOGY, 1980, 8 (03) :207-209
[10]  
GUTMAN FA, 1974, T AM ACAD OPHTHALMOL, V78, pO178