The Second European Evidenced-Based Consensus on Reproduction and Pregnancy in Inflammatory Bowel Disease

被引：359

作者：

van der Woude, C. J. ^{[1
]}

Ardizzone, S. ^{[2
]}

Bengtson, M. B. ^{[3
]}

Fiorino, G. ^{[4
]}

Fraser, G. ^{[5
,6
]}

Katsanos, K. ^{[7
]}

Kolacek, S. ^{[8
]}

Juillerat, P. ^{[9
]}

Mulders, A. G. M. G. J. ^{[10
]}

Pedersen, N. ^{[11
]}

Selinger, C. ^{[12
]}

Sebastian, S. ^{[13
,14
]}

Sturm, A. ^{[15
]}

Zelinkova, Z. ^{[16
]}

Magro, F. ^{[17
,18
,19
]}

机构：

[1] Erasmus MC, Dept Gastroenterol & Hepatol, NL-3015 CE Rotterdam, Netherlands

[2] Luigi Sacco Univ Hosp, Dept Gastroenterol, Inflammatory Bowel Dis Unit, Milan, Italy

[3] Vestfold Hosp Trust, Dept Med, Tonsberg, Norway

[4] IRCCS Ist Clin Humanitas, IBD Ctr, Dept Gastroenterol, Rozzano, Italy

[5] Rabin Med Ctr, Dept Gastroenterol, IBD Unit, Petah Tiqwa, Israel

[6] Tel Aviv Univ, Petah Tiqwa, Israel

[7] Univ & Med Sch Ioannina, Dept Gastroenterol & Hepatol, Ioannina, Greece

[8] Univ Zagreb, Sch Med, Childrens Hosp Zagreb, Zagreb 41000, Croatia

[9] Univ Hosp Bern, Clin Visceral Surg & Med, Dept Gastroenterol, CH-3010 Bern, Switzerland

[10] Erasmus MC, Dept Obstet & Gynecol, NL-3015 CE Rotterdam, Netherlands

[11] Herlev Univ Hosp, Gastroenterol Unit, DK-2730 Herlev, Denmark

[12] St James Univ Hosp, Dept Gastroenterol, Leeds LS9 7TF, W Yorkshire, England

[13] Hull & East Yorkshire Hosp, Kingston Upon Hull, N Humberside, England

[14] Hull & York Med Sch, Kingston Upon Hull, N Humberside, England

[15] Hosp Waldfriede, Dept Internal Med & Gastroenterol, Berlin, Germany

[16] Univ Hosp, Dept Internal Med 5, Gastroenterol Unit, Bratislava, Slovakia

[17] Univ Porto, Dept Pharmacol & Therapeut, P-4100 Oporto, Portugal

[18] Univ Porto, Ctr Drug Discovery & Innovat Med, MedInUP, P-4100 Oporto, Portugal

[19] Hosp Sao Joao, Dept Gastroenterol, Oporto, Portugal

来源：

JOURNAL OF CROHNS & COLITIS | 2015年 / 9卷 / 02期

关键词：

Inflammatory bowel disease; pregnancy; reproduction; lactation; Crohn's disease; ulcerative colitis; POUCH-ANAL ANASTOMOSIS; ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY; QUALITY-OF-LIFE; PERIANAL CROHNS-DISEASE; ORAL-CONTRACEPTIVE USE; ULCERATIVE-COLITIS; SEXUAL FUNCTION; RESTORATIVE PROCTOCOLECTOMY; BIRTH OUTCOMES; BREAST-MILK;

D O I：

10.1093/ecco-jcc/jju006

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Trying to conceive and being pregnant is an emotional period for those involved. In the majority of patients suffering from inflammatory bowel disease, maintenance therapy is required during pregnancy to control the disease, and disease control might necessitate introduction of new drugs during a vulnerable period. In this updated consensus on the reproduction and pregnancy in inflammatory bowel disease reproductive issues including fertility, the safety of drugs during pregnancy and lactation are discussed.

引用

页码：107 / 124

页数：18

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