Skipping breakfast during pregnancy and hypertensive disorders of pregnancy in Japanese women: the Tohoku medical megabank project birth and three-generation cohort study

被引：6

作者：

Aizawa, Misato ^{[1
]}

Murakami, Keiko ^{[1
,2
]}

Takahashi, Ippei ^{[1
]}

Onuma, Tomomi ^{[2
]}

Noda, Aoi ^{[1
,2
,3
]}

Ueno, Fumihiko ^{[1
,2
]}

Matsuzaki, Fumiko ^{[1
,2
]}

Ishikuro, Mami ^{[1
,2
]}

Obara, Taku ^{[1
,2
,3
]}

Hamada, Hirotaka ^{[1
,4
]}

Iwama, Noriyuki ^{[1
,2
,4
]}

Saito, Masatoshi ^{[1
,4
]}

Sugawara, Junichi ^{[1
,2
,4
]}

Yaegashi, Nobuo ^{[1
,2
,4
]}

Kuriyama, Shinichi ^{[1
,2
,5
]}

机构：

[1] Tohoku Univ, Grad Sch Med, Sendai, Miyagi, Japan

[2] Tohoku Univ, Tohoku Med Megabank Org, Sendai, Miyagi, Japan

[3] Tohoku Univ Hosp, Dept Pharmaceut Sci, Sendai, Miyagi, Japan

[4] Tohoku Univ Hosp, Dept Obstet & Gynecol, Sendai, Miyagi, Japan

[5] Tohoku Univ, Int Res Inst Disaster Sci, Sendai, Miyagi, Japan

来源：

NUTRITION JOURNAL | 2022年 / 21卷 / 01期

关键词：

Skipping breakfast; Hypertensive disorders of pregnancy; Preeclampsia; Japan; Circadian clock; DIETARY PATTERNS; BLOOD-PRESSURE; SOCIAL JETLAG; ENERGY-INTAKE; ASSOCIATION; ENVIRONMENT; METABOLISM; RISK; TIME; FOOD;

D O I：

10.1186/s12937-022-00822-9

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Background Hypertensive disorders of pregnancy (HDP) adversely affect the prognosis of mother and child, and the prognosis depends on the subtype of HDP. Skipping breakfast may be associated with increased blood pressure due to disruption of the circadian clock, but the association with the development of HDP has not been studied. The purpose of this study was to examine the association between skipping breakfast and the development of HDP and HDP subtypes in Japanese pregnant women. Methods Of the pregnant women who participated in the Tohoku Medical Megabank Project Three-Generation Cohort Study, 18,839 who answered the required questions were included in the analysis. This study had a cross-sectional design. The breakfast intake frequency from pre-pregnancy to early pregnancy was classified into four groups: daily, 5-6 times per week, 3-4 times per week, and 0-2 times per week. HDP was classified into gestational hypertension (GH), chronic hypertension (CH), preeclampsia (PE), and severe preeclampsia (SuPE). Multiple logistic regression analysis and multinomial logistic analysis were used to calculate odds ratios (ORs) and 95% confidence intervals (CIs) for breakfast intake frequency and development of HDP or HDP subtypes. We performed a stratified analysis based on energy intake. Results Of the participants, 74.3% consumed breakfast daily, and 11.1% developed HDP. Women who consumed breakfast 0-2 times per week had a higher risk of HDP (OR: 1.33, 95% CI: 1.14-1.56), CH (OR: 1.63, 95% CI: 1.21-2.19), and PE (OR: 1.68, 95% CI: 1.27-2.21) than those who consumed breakfast daily. No association was found between skipping breakfast and the risk of developing GH (OR: 1.26, 95% CI: 0.99-1.61) and SuPE (OR: 0.91, 95% CI: 0.55-1.49). Stratified analysis showed that the risk of developing HDP due to skipping breakfast was highest in the group with the highest daily energy intake. Conclusions Skipping breakfast during pre-to early pregnancy is associated with the development of HDP. Further longitudinal studies are required to clarify the causal association between skipping breakfast and HDP.

引用

页数：10

共 51 条

[1] Prevalence of dysmenorrhea and predictors of its pain intensity among Palestinian female university students [J].