Wild great apes as sentinels and sources of infectious disease

被引:87
作者
Calvignac-Spencer, S. [1 ]
Leendertz, S. A. J. [1 ]
Gillespie, T. R. [2 ,3 ,4 ]
Leendertz, F. H. [1 ]
机构
[1] Robert Koch Inst, D-13353 Berlin, Germany
[2] Emory Univ, Dept Environm Studies, Atlanta, GA 30322 USA
[3] Emory Univ, Program Populat Biol Ecol & Evolut, Atlanta, GA 30322 USA
[4] Emory Univ, Dept Environm Hlth, Rollins Sch Publ Hlth, Atlanta, GA 30322 USA
关键词
Chimpanzee; disease ecology; emerging infectious diseases; gorilla; zoonoses; PAN-TROGLODYTES-TROGLODYTES; MOUNTAIN GORILLAS; VIRUS; CHIMPANZEES; WESTERN; TRANSMISSION; ORIGIN; EBOLA; AIDS; CONSERVATION;
D O I
10.1111/j.1469-0691.2012.03816.x
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Clin Microbiol Infect 2012; 18: 521527 Abstract Emerging zoonotic infectious diseases pose a serious threat to global health. This is especially true in relation to the great apes, whose close phylogenetic relationship with humans results in a high potential for microorganism exchange. In this review, we show how studies of the microorganisms of wild great apes can lead to the discovery of novel pathogens of importance for humans. We also illustrate how these primates, living in their natural habitats, can serve as sentinels for outbreaks of human disease in regions with a high likelihood of disease emergence. Greater sampling efforts and improvements in sample preservation and diagnostic capacity are rapidly improving our understanding of the diversity and distribution of microorganisms in wild great apes. Linking non-invasive diagnostic data with observational health data from great apes habituated to human presence is a promising approach for the discovery of pathogens of high relevance for humans.
引用
收藏
页码:521 / 527
页数:7
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