Acute Kidney Injury in Children

被引:52
作者
Sutherland, Scott M.
Kwiatkowski, David M.
机构
[1] Stanford Univ, Dept Pediat, Div Nephrol, Palo Alto, CA 94304 USA
[2] Stanford Univ, Dept Pediat, Div Cardiol, Palo Alto, CA 94304 USA
关键词
Acute kidney injury; Child; Pediatrics; RENAL REPLACEMENT THERAPY; CRITICALLY-ILL CHILDREN; CONGENITAL HEART-SURGERY; HOSPITALIZED CHILDREN; CARDIAC-SURGERY; LONG-TERM; FOLLOW-UP; INITIAL-EXPERIENCE; SERUM CREATININE; YOUNG-ADULTS;
D O I
10.1053/j.ackd.2017.09.007
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Acute kidney injury (AKI) has become one of the more common complications seen among hospitalized children. The development of a consensus definition has helped refine the epidemiology of pediatric AKI, and we now have a far better understanding of its incidence, risk factors, and outcomes. Strategies for diagnosing AKI have extended beyond serum creatinine, and the most current data underscore the diagnostic importance of oliguria as well as introduce the concept of urinary biomarkers of kidney injury. As AKI has become more widespread, we have seen that it is associated with a number of adverse consequences including longer lengths of stay and greater mortality. Though effective treatments do not currently exist for AKI once it develops, we hope that the diagnostic and definitional strides seen recently translate to the testing and development of more effective interventions. (C) 2017 by the National Kidney Foundation, Inc. All rights reserved.
引用
收藏
页码:380 / 387
页数:8
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