Actin-Based Motility of Listeria: Right-Handed Helical Trajectories

被引：0
|
作者：
Rangarajan, Murali [1 ]
机构：
[1] Amrita Vishwa Vidyapeetham, Dept Chem Engn & Mat Sci, Coimbatore 641112, Tamil Nadu, India
来源：
SOLID STATE PHYSICS, PTS 1 AND 2 | 2012年 / 1447卷
关键词：
actin; cell motility; Listeria; molecular motors; FORCE GENERATION; FILAMENTS; MODEL;
D O I：
10.1063/1.4709932
中图分类号：
O59 [应用物理学];
学科分类号：
摘要：
Bacteria such as Listeria monocytogenes recruit cellular machinery to move in and between cells. Understanding the mechanism of motility, including force and torque generation and the resultant displacements, holds keys to numerous applications in medicine and biosensing. In this work, a simple back-of-the-envelope calculation is presented to illustrate that a biomechanical model of actin-based motility of a rigid surface through persistently attached filaments propelled by affinity-modulated molecular motors can produce a right-handed helical trajectory consistent with experimental observations. The implications of the mechanism to bacterial motility are discussed.
引用
收藏
页码：165 / 166
页数：2
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