Lithium perchlorate-catalyzed regioselective ring-opening of aziridines with potassium thiocyanate

被引：17

作者：

Yadav, JS ^{[1
]}

Reddy, BVS ^{[1
]}

Jyothirmai, B ^{[1
]}

Murty, MSR ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Div Organ Chem, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 37期

关键词：

lithium perchlorate; aziridines; potassium thiocyanate; beta-aminothiocyanates;

D O I：

10.1016/j.tetlet.2005.06.165

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Aziridines react smoothly with potassium thiocyanate in the presence of a catalytic amount of lithium perchlorate in acetonitrile under mild reaction conditions to afford the corresponding beta-aminothiocyanates in high yields and with high regioselectivity. The combination of lithium perchlorate and acetonitrile provides a convenient catalytic medium to perform the reactions under neutral conditions. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：6385 / 6387

页数：3

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