Five-year point prevalence survey of healthcare- associated infections and antimicrobial use in a Japanese university hospital

被引：4

作者：

Morioka, H. ^{[1
,12
]}

Iguchi, M. ^{[1
]}

Tetsuka, N. ^{[1
]}

Kinoshita, F. ^{[2
]}

Tomita, Y. ^{[1
,3
]}

Kato, D. ^{[1
,4
]}

Hirabayashi, A. ^{[1
,5
]}

Matsumoto, A. ^{[1
]}

Oka, K. ^{[1
]}

Kato, H. ^{[1
,6
]}

Inagaki, T. ^{[7
]}

Kato, Y. ^{[7
]}

Kitagawa, K. ^{[7
]}

Ichikawa, K. ^{[7
,8
]}

Kouyama, Y. ^{[9
]}

Kawamura, N. ^{[10
]}

Toyodome, Y. ^{[10
]}

Adachi, N. ^{[10
]}

Ito, Y. ^{[11
]}

Yagi, T. ^{[1
]}

机构：

[1] Nagoya Univ Hosp, Dept Infect Dis, Aichi, Japan

[2] Nagoya Univ Hosp, Dept Adv Med, Aichi, Japan

[3] Japanese Red Cross Nagoya Daini Hosp, Dept Internal Med, Aichi, Japan

[4] Okazaki City Hosp, Dept Orthoped Surg, Aichi, Japan

[5] Natl Inst Infect Dis, Antimicrobial Resistance Res Ctr, Tokyo, Japan

[6] Toyota Mem Hosp, Dept Infect Dis, Aichi, Japan

[7] Nagoya Univ Hosp, Dept Hosp Pharm, Aichi, Japan

[8] NHO Mie Chuo Med Ctr, Dept Pharm, Mie, Japan

[9] Fujita Hlth Univ Hosp, Dept Pharm, Aichi, Japan

[10] Nagoya Univ Hosp, Dept Nursing, Aichi, Japan

[11] Nagoya Univ, Dept Pediat, Grad Sch Med, Nagoya, Aichi, Japan

[12] Nagoya Univ Hosp, Dept Infect Dis, 65 Tsurumai Cho,Showa Ku, Nagoya, Aichi 4668550, Japan

来源：

INFECTION PREVENTION IN PRACTICE | 2021年 / 3卷 / 03期

关键词：

Point prevalence survey; Healthcare-associated infection; Antimicrobial stewardship; Surgical antimicrobial prophylaxis; GUIDELINES;

D O I：

10.1016/j.infpip.2021.100151

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Background: Periodic point prevalence surveys (PPSs) provide a method for assessing changes in healthcare-associated infections (HAIs) and antimicrobial use over time. Fol-lowing the introduction of an antimicrobial stewardship programme at Nagoya University Hospital (Aichi, Japan) a five-year PPS study was performed to highlight any epidemio-logical changes.Methods: One-day PPSs were performed annually in July at Nagoya University Hospital. Data on patient characteristics, medical devices, active HAIs and antimicrobial use were collected using a standard data-collection form.Results: A total of 4339 patients were included. Over the five-year study period the median patient age was 62 years, median duration of hospital admission was nine days, 9% of patients had an HAI and 35.2% received at least one antimicrobial. Overall there were 406 HAIs (95% confidence interval, 369e447) with surgical site infection, pneumonia and febrile neutropenia occurring most frequently. Enterobacterales were the most common pathogens (N 1/4 78, 28.6%) and 32.1% were third-generation cephalosporin-resistant. Meropenem was the most frequently prescribed antimicrobial for HAIs. Surgical anti-microbial prophylaxis changed drastically, with shorter durations and a marked reduction in oral cephalosporin use. However, antimicrobials for medical prophylaxis gradually increased.Conclusions: This five-year PPS study shows consistent data for patient background, HAIs and causative pathogens and highlights changes in antimicrobial use during the era of the National Action Plan on Antimicrobial Resistance. To describe the epidemiology of Japa-nese hospitals by PPS, multicentre PPSs including in community hospitals should be per-formed annually. 2021 The Authors. Published by Elsevier Ltd on behalf of The Healthcare Infection Society. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

引用

页数：7

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