Microbial transformation of prenylflavonoids from Psoralea corylifolia by using Cunninghamella blakesleeana and C. elegans

被引：9

作者：

Ma, Shunan ^{[1
]}

Zheng, Cheng ^{[1
]}

Feng, Li ^{[1
]}

Huang, Youwu ^{[1
]}

Wang, Rui ^{[1
]}

Huang, Cheng ^{[1
]}

Li, Yiming ^{[1
]}

Guo, Fujiang ^{[1
]}

机构：

[1] Shanghai Univ Tradit Chinese Med, Sch Pharm, Shanghai 201203, Peoples R China

来源：

JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC | 2015年 / 118卷

基金：

上海市自然科学基金;

关键词：

Biotransformation; Prenylflavonoids; Cunninghamella blakesleeana; Cunninghamella elegans; PRENYLATED FLAVONOIDS; ASPERGILLUS-NIGER; DERIVATIVES; L;

D O I：

10.1016/j.molcatb.2015.04.015

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Cunninghamella blakesleeana AS 3.0970 and AS 3.0910 and C. elegans AS 3.2028 were first used for biotransforming three major prenylflavonoids from Psoralea corylifolia, namely bavachinin, bavachin, and isobavachalcone. A total of seven biotransformation products, including six new compounds, were obtained and identified. The agonistic activities of peroxisome proliferator-activated receptor-gamma against substrates and biotransformation products were also evaluated. (C) 2015 Elsevier B.V. All rights reserved.

引用

页码：8 / 15

页数：8

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