Initiation of plant disease resistance by physical interaction of AvrPto and Pto kinase

被引：512
作者：
Tang, XY
Frederick, RD
Zhou, JM
Halterman, DA
Jia, YL
Martin, GB
机构：
[1] Department of Agronomy, Purdue University, West Lafayette
来源：
SCIENCE | 1996年 / 274卷 / 5295期
关键词：
D O I：
10.1126/science.274.5295.2060
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Resistance to bacterial speck disease in tomato occurs when the Pto kinase in the plant responds to expression of the avirulence gene avrPto in the Pseudomonas pathogen. Transient expression of an avrPto transgene in plant cells containing Pto elicited a defense response. In the yeast two-hybrid system, the Pto kinase physically interacted with AvrPto. Alterations of AvrPto or Pto that disrupted the interaction in yeast also abolished disease resistance in plants. The physical interaction of AvrPto and Pto provides an explanation of gene-for-gene specificity in bacterial speck disease resistance.
引用
收藏
页码：2060 / 2063
页数：4
相关论文
共 34 条
[1]   RPS2 OF ARABIDOPSIS-THALIANA - A LEUCINE-RICH REPEAT CLASS OF PLANT-DISEASE RESISTANCE GENES [J].
BENT, AF ;
KUNKEL, BN ;
DAHLBECK, D ;
BROWN, KL ;
SCHMIDT, R ;
GIRAUDAT, J ;
LEUNG, J ;
STASKAWICZ, BJ .
SCIENCE, 1994, 265 (5180) :1856-1860
[2]   THE ROLE OF HOST TYROSINE PHOSPHORYLATION IN BACTERIAL PATHOGENESIS [J].
BLISKA, JB ;
FALKOW, S .
TRENDS IN GENETICS, 1993, 9 (03) :85-89
[3]   ULTRASTRUCTURE OF INTERACTIONS BETWEEN XANTHOMONAS-CAMPESTRIS PV VESICATORIA AND PEPPER, INCLUDING IMMUNOCYTOCHEMICAL LOCALIZATION OF EXTRACELLULAR POLYSACCHARIDES AND THE AVRBS3 PROTEIN [J].
BROWN, I ;
MANSFIELD, J ;
IRLAM, I ;
CONRADSSTRAUCH, J ;
BONAS, U .
MOLECULAR PLANT-MICROBE INTERACTIONS, 1993, 6 (03) :376-386
[4]  
Dangl J L, 1994, Curr Top Microbiol Immunol, V192, P99
[5]   The tomato Cf-2 disease resistance locus comprises two functional genes encoding leucine-rich repeat proteins [J].
Dixon, MS ;
Jones, DA ;
Keddie, JS ;
Thomas, CM ;
Harrison, K ;
Jones, JDG .
CELL, 1996, 84 (03) :451-459
[6]  
ELLINGBOE A, 1980, ACTIVE DEFENSE MECH, P179
[7]   CURRENT STATUS OF GENE-FOR-GENE CONCEPT [J].
FLOR, HH .
ANNUAL REVIEW OF PHYTOPATHOLOGY, 1971, 9 :275-+
[8]  
FREDERICK RD, UNPUB
[9]   WORKING MODELS OF SPECIFIC RECOGNITION IN PLANT-MICROBE INTERACTIONS [J].
GABRIEL, DW ;
ROLFE, BG .
ANNUAL REVIEW OF PHYTOPATHOLOGY, 1990, 28 :365-391
[10]   A SECRETED PROTEIN-KINASE OF YERSINIA-PSEUDOTUBERCULOSIS IS AN INDISPENSABLE VIRULENCE DETERMINANT [J].
GALYOV, EE ;
HAKANSSON, S ;
FORSBERG, A ;
WOLFWATZ, H .
NATURE, 1993, 361 (6414) :730-732
1234