A new picrotoxane sesquiterpene from the berries of Baccaurea ramiflora with antifungal activity against Colletotrichum gloeosporioides

被引：16

作者：

Pan, Zheng-Hong ^{[1
]}

Ning, De-Sheng ^{[1
]}

Huang, Si-Si ^{[1
]}

Wu, Yun-Fei ^{[2
]}

Ding, Tao ^{[1
]}

Luo, Lei ^{[2
]}

机构：

[1] Guangxi Zhuang Autonomous Reg & Chinese Acad Sci, Guangxi Inst Bot, Guangxi Key Lab Funct Phytochem Res & Utilizat, Guilin 541006, Peoples R China

[2] Yunnan Normal Univ, Fac Chem & Chem Engn, Kunming 650500, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2015年 / 29卷 / 14期

基金：

中国国家自然科学基金;

关键词：

ramifloside; sesquiterpene glycoside; Baccaurea ramiflora; picrotoxane; antifungal activity;

D O I：

10.1080/14786419.2014.999335

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Three picrotoxane sesquiterpenes including one new glycoside and two known constituents, sapidolide A (2) and picrotoximaesin (3), were isolated from the berries of Baccaurea ramiflora. The structure of the new sesquiterpene glycoside, ramifloside (1), was elucidated as 2-one-6 alpha-hydroxy-13-nor-11-picrotoxen-3(15 beta)-olide 10-O-beta-d-glucopyranoside on the basis of extensive spectroscopic analysis. Compounds 1-3 exhibited antifungal activity against Colletotrichum gloeosporioides with MICs of 12.5, 12.5 and 50 mu g/mL.

引用

页码：1323 / 1327

页数：5

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