Serum omentin-1 levels are inversely associated with the presence and severity of coronary artery disease in patients with metabolic syndrome

被引:89
|
作者
Shang, Fu-Jun [1 ]
Wang, Jie-Pin [2 ]
Liu, Xiong-Tao [1 ]
Zheng, Qiang-Sun [1 ]
Xue, Yu-Sheng [1 ]
Wang, Bin [1 ]
Zhao, Lian-You [1 ]
机构
[1] Fourth Mil Med Univ, Dept Cardiol, Tangdu Hosp, Xian 710038, Shaanxi, Peoples R China
[2] Fourth Mil Med Univ, Dept Pharm, Tangdu Hosp, Xian 710038, Shaanxi, Peoples R China
关键词
Adipokines; biomarker; cardiometabolic syndrome; coronary atherosclerosis index; CHOLESTEROL; INFLAMMATION; ADIPOKINES; MORTALITY;
D O I
10.3109/1354750X.2011.622789
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Context: Omentin-1, an adipokine secreted from visceral adipose tissue, has been reported to be associated with coronary artery disease (CAD) and metabolic disorders. Objective: To clarify the relationship between serum omentin-1 levels and the presence and severity of CAD in patients with metabolic syndrome (MetS). Methods: We measured serum omentin-1 levels in 175 consecutive patients with MetS and in 46 controls. Results: Serum omentin-1 levels are inversely associated with the presence and angiographic severity of CAD in MetS patients. Conclusions: Serum omentin-1 might be a potential biomarker to predict the development and progression of CAD in MetS patients.
引用
收藏
页码:657 / 662
页数:6
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