Multiple abscesses in immunocompetent patients caused by Panton-Valentine-leukocidin-positive Staphylococcus aureus

被引:6
作者
Vonberg, R. -P. [1 ]
Sedlacek, L. [1 ]
Chaberny, I. F. [1 ]
Suerbaum, S. [1 ]
Gastmeier, P. [1 ]
Linde, H. -J. [2 ]
机构
[1] Hannover Med Sch, Inst Med Mikrobiol & Krankenhaushyg, D-30625 Hannover, Germany
[2] Univ Regensburg, Inst Med Mikrobiol & Hyg, D-8400 Regensburg, Germany
来源
HAUTARZT | 2008年 / 59卷 / 04期
关键词
PVL; S; aureus; abscess; pneumonia; infection control measures;
D O I
10.1007/s00105-007-1374-1
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
We report cases of immunocompetent patients showing multiple abscesses by a Panton-Valentine leukocidin (PVL) positive Staphylococcus aureus. PVL is considered to be an important virulence factor. The most common manifestations by this pathogen are recurrent or multiple abscesses of the skin. Seldom necrotizing pneumonia with high mortality occurs. Even methicillin-resistant PVL positive isolates have been identified in Germany. Only appropriate infection control measures in combination with antimicrobial therapy resulted in successful eradication of this pathogen. Dermatologists should be informed about this specific type of infection and about the appropriate infection control measures.
引用
收藏
页码:319 / 322
页数:4
相关论文
共 11 条
  • [1] Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients
    Gillet, Y
    Issartel, B
    Vanhems, P
    Fournet, JC
    Lina, G
    Bes, M
    Vandenesch, F
    Piémont, Y
    Brousse, N
    Floret, D
    Etienne, J
    [J]. LANCET, 2002, 359 (9308) : 753 - 759
  • [2] Frequent carriage of Panton-Valentine leucocidin genes by Staphylococcus aureus isolates from surgically drained abscesses
    Issartel, B
    Tristan, A
    Lechevallier, S
    Bruyère, F
    Lina, G
    Garin, B
    Lacassin, F
    Bes, M
    Vandenesch, F
    Etienne, J
    [J]. JOURNAL OF CLINICAL MICROBIOLOGY, 2005, 43 (07) : 3203 - 3207
  • [3] Complete nucleotide sequence and molecular characterization of the temperate staphylococcal bacteriophage φPVL carrying Panton-Valentine leukocidin genes
    Kaneko, J
    Kimura, T
    Narita, S
    Tomita, T
    Kamio, Y
    [J]. GENE, 1998, 215 (01) : 57 - 67
  • [4] Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia
    Lina, G
    Piémont, Y
    Godail-Gamot, F
    Bes, M
    Peter, MO
    Gauduchon, V
    Vandenesch, F
    Etienne, J
    [J]. CLINICAL INFECTIOUS DISEASES, 1999, 29 (05) : 1128 - 1132
  • [5] Healthcare-associated outbreaks and community-acquired infections due to MRSA carrying the Panton-Valentine leucocidin gene in southeastern Germany
    Linde, H
    Wagenlehner, F
    Strommenger, B
    Drubel, I
    Tanzer, J
    Reischl, U
    Raab, U
    Höller, C
    Naber, KG
    Witte, W
    Hanses, F
    Salzberger, B
    Lehn, N
    [J]. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2005, 24 (06) : 419 - 422
  • [6] Community-acquired, methicillin-resistant and methicillin-susceptible Staphylococcus aureus musculoskeletal infections in children
    Martínez-Aguilar, G
    Avalos-Mishaan, A
    Hulten, K
    Hammerman, W
    Mason, EO
    Kaplan, SL
    [J]. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2004, 23 (08) : 701 - 706
  • [7] Prevalence of and risk factors for carriage of Panton-Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus among residents and staff of a German nursing home
    Raab, Ulla
    Kahlau, Dagmar
    Wagenlehner, Florian
    Reischl, Udo
    Ehrenstein, Vera
    Lehn, Norbert
    Hoeller, Christiane
    Linde, Hans-Jorg
    [J]. INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2006, 27 (02) : 208 - 211
  • [8] Panton valentine leukocidin (PVL) toxin positive MRSA strains isolated from companion animals
    Rankin, S
    Roberts, S
    O'Shea, K
    Maloney, D
    Lorenzo, M
    Benson, CE
    [J]. VETERINARY MICROBIOLOGY, 2005, 108 (1-2) : 145 - 148
  • [9] WIESEPOSSELT M, 2005, EPIDEMIOL B, V10, P79
  • [10] Witte W, 2005, HAUTARZT, V56, P731, DOI 10.1007/s00105-005-0975-9