Clinical and Laboratory Characteristics of Invasive Infections Due to Methicillin-Resistant Staphylococcus aureus Isolates Demonstrating a Vancomycin MIC of 2 Micrograms per Milliliter: Lack of Effect of Heteroresistant Vancomycin-Intermediate S. aureus Phenotype

被引:22
作者
Satola, S. W. [1 ,2 ]
Lessa, F. C. [3 ]
Ray, S. M. [2 ]
Bulens, S. N. [3 ,4 ]
Lynfield, R. [5 ]
Schaffner, W. [6 ]
Dumyati, G. [7 ]
Nadle, J. [8 ]
Patel, J. B. [3 ]
机构
[1] Atlanta VA Med Ctr, Decatur, GA 30033 USA
[2] Emory Univ, Sch Med, Atlanta, GA USA
[3] Ctr Dis Control, Div Healthcare Qual Promot, Atlanta, GA 30333 USA
[4] Atlanta Res & Educ Fdn, Atlanta, GA USA
[5] Minnesota Dept Hlth, St Paul, MN USA
[6] Vanderbilt Univ, Sch Med, Nashville, TN 37212 USA
[7] Univ Rochester, Rochester, NY USA
[8] Calif Emerging Infect Program, Oakland, CA USA
关键词
UNITED-STATES; BACTEREMIA; MRSA; SUSCEPTIBILITY; FEATURES; OUTCOMES; PERIOD;
D O I
10.1128/JCM.01719-10
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We describe clinical and laboratory characteristics of invasive methicillin-resistant Staphylococcus aureus (MRSA) infections with vancomycin MICs of 2 mu g/ml and compare heteroresistant-intermediate S. aureus (hVISA) to non-hVISA. Health care-associated community-onset infections were the most common and resulted in frequent complications and relapses. hVISA-infected patients were more likely to have been hospitalized in the year prior to MRSA culture.
引用
收藏
页码:1583 / 1587
页数:5
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