Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein

被引:467
作者
Xia, Shuai [1 ]
Zhu, Yun [2 ]
Liu, Meiqin [3 ]
Lan, Qiaoshuai [1 ]
Xu, Wei [1 ]
Wu, Yanling [1 ]
Ying, Tianlei [1 ]
Liu, Shuwen [4 ]
Shi, Zhengli [3 ]
Jiang, Shibo [1 ,5 ]
Lu, Lu [1 ]
机构
[1] Fudan Univ, Sch Basic Med Sci, Fudan Jinbo Joint Res Ctr, Key Lab Med Mol Virol MOE NHC CAMS, Shanghai, Peoples R China
[2] Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, Beijing, Peoples R China
[3] Chinese Acad Sci, Wuhan Inst Virol, CAS Key Lab Special Pathogens & Biosafety, Wuhan, Peoples R China
[4] Southern Med Univ, Guangzhou Key Lab Drug Res Emerging Virus Prevent, Sch Pharmaceut Sci, Guangdong Prov Key Lab New Drug Screening, Guangzhou, Peoples R China
[5] New York Blood Ctr, Lindsley F Kimball Res Inst, New York, NY 10021 USA
关键词
CORONAVIRUS;
D O I
10.1038/s41423-020-0374-2
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:765 / 767
页数:3
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