Candida kefyr as a cause of bloodstream infection and adjunctive role of biomarkers in its diagnosis

被引：13
作者：
Khan, Z. [1 ]
Ahmad, S. [1 ]
Al-Obaid, K. [2 ]
Joseph, L. [1 ]
Chandy, R. [1 ]
机构：
[1] Kuwait Univ, Fac Med, Dept Microbiol, Safat 1311, Kuwait
[2] Al Amiri Hosp, Microbiol Unit, Kuwait, Kuwait
来源：
JOURNAL DE MYCOLOGIE MEDICALE | 2015年 / 25卷 / 01期
关键词：
Candida kefyr; beta-D-glucan; Candida mannan; Candida DNA; Kuwait; ANTIFUNGAL SUSCEPTIBILITY; INVASIVE CANDIDIASIS; EMERGING PATHOGEN; FUNGEMIA; LEUKEMIA; UNCOMMON; PATIENT; RAPD; PCR;
D O I：
10.1016/j.mycmed.2014.04.002
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
A rare case of bloodstream infection caused by Candida kefyr is described. The diagnosis was established by repeatedly isolating the yeast in blood cultures and by detecting C. kefyr-specific DNA in serum samples. Demonstration of elevated serum levels of beta-D-glucan and Candida mannan also provided additional diagnostic evidence. The identity of the isolates was confirmed by PCR sequencing of the ITS region of rDNA. This is the first report of C. kefyr candidemia from Kuwait and the Middle East. The report highlights emerging clinical significance of rare Candida spp. in etiology of candidemia and reinforces the adjunctive role of biomarkers in diagnosis. (C) 2014 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：71 / 75
页数：5
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