Rectal microbicides for US gay men -: Are clinical trials needed?: Are they feasible?

被引：51

作者：

Gross, M

Buchbinder, SP

Celum, C

Heagerty, P

Seage, GR

机构：

[1] ABT Associates Inc, Bethesda, MD 20814 USA

[2] ABT Associates Inc, Cambridge, MA 02138 USA

[3] San Francisco Dept Publ Hlth, Dept Publ Hlth, AIDS Off, San Francisco, CA USA

[4] Harborview Med Ctr, Seattle, WA USA

[5] Univ Washington, Seattle, WA 98195 USA

[6] Fred Hutchinson Canc Res Ctr, Seattle, WA 98104 USA

[7] Boston Univ, Sch Publ Hlth, Dept Epidemiol & Biostat, Boston, MA USA

来源：

SEXUALLY TRANSMITTED DISEASES | 1998年 / 25卷 / 06期

关键词：

D O I：

10.1097/00007435-199807000-00005

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Background and Objectives: Incomplete condom use during anal sex persists among gay men; microbicides may provide additional protection. Despite the absence of efficacy or safety data, many gay men use sexual lubricants containing nonoxynol-9 (N-9), a detergent-based spermicide under evaluation for efficacy as a vaginal microbicide. Goal: Evaluate unprotected sex, lubricant use, and attitudes regarding possible participation in clinical trials of rectal microbicides among high-risk human immunodeficiency virus(HIV) seronegative U.S. gay men in six cities.

引用

页码：296 / 302

页数：7

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