1H, 13C and 15N resonance assignments of TbBDF5-bromo1 domain from Trypanosoma brucei

被引：0
|
作者：
Yang, Li [1 ]
Zhang, Xiaole [1 ]
Zhang, Jiahai [1 ]
Tu, Xiaoming [1 ]
机构：
[1] Univ Sci & Technol China, Sch Life Sci, MOE Key Lab Membraneless Organelles & Cellular Dy, Hefei 230027, Anhui, Peoples R China
来源：
BIOMOLECULAR NMR ASSIGNMENTS | 2022年 / 16卷 / 02期
关键词：
Trypanosoma brucei; Bromo domain; TbBDF5; Resonance assignment; BROMODOMAIN;
D O I：
10.1007/s12104-022-10088-1
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
H-1, C-13 and N-15 resonance assignments are presented for the first bromo domain of TbBDF5 (TbBDF5-bromo1) from Trypanosoma brucei. TbBDF5 is localized in the nucleus and plays a potential role in transcription regulation. Bromo domains can recognize acetylated histone through a conserved binding pocket. Here we report the NMR resonance assignments of TbBDF5-bromo1 domain for further studies of the relationship between its structure and function.
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页码：253 / 255
页数：3
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