Common threads in eukaryotic circadian systems

被引：36

作者：

Dunlap, JC ^{[1
]}

机构：

[1] Dartmouth Med Sch, Dept Biochem, Hanover, NH 03755 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1998年 / 8卷 / 04期

关键词：

D O I：

10.1016/S0959-437X(98)80109-3

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Within the past 18 months, common regulatory patterns have emerged among eukaryotic circadian systems - extending from fungi through to mammals. Heterodimeric complexes of PAS-domain-containing transcription factors play positive roles in clack-associated feedback loops, and classic clock proteins like FREQUENCY (FRQ), PERIOD (PER), and TIMELESS (TIM) appear as negative elements. Post-transcriptional control governs the amount and type of FRQ and makes the clock responsive to temperature.

引用

页码：400 / 406

页数：7

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