Next Generation Prokaryotic Engineering: The CRISPR-Cas ToolKit

被引：89

作者：

Mougiakos, Ioannis ^{[1
]}

Bosma, Elleke F. ^{[1
]}

de Vos, Willem M. ^{[1
]}

van Kranenburg, Richard ^{[1
,2
]}

van der Oost, John ^{[1
]}

机构：

[1] Wageningen Univ, Microbiol Lab, Dreijenpl 10, NL-6703 HB Wageningen, Netherlands

[2] Corbion, Arkelsedijk 46, NL-4206 AC Gorinchem, Netherlands

来源：

TRENDS IN BIOTECHNOLOGY | 2016年 / 34卷 / 07期

关键词：

SEQUENCE-SPECIFIC ANTIMICROBIALS; ESCHERICHIA-COLI; GENE-EXPRESSION; STREPTOCOCCUS-THERMOPHILUS; SYSTEM; RNA; GENOME; DNA; IMMUNITY; REPRESSION;

D O I：

10.1016/j.tibtech.2016.02.004

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The increasing demand for environmentally friendly production processes of green chemicals and fuels has stimulated research in microbial metabolic engineering. CRISPR-Cas-based tools for genome editing and expression control have enabled fast, easy, and accurate strain development for established production platform organisms, such as Escherichia coli and Saccharomyces cerevisiae. However, the growing interest in alternative production hosts, for which genome editing options are generally limited, requires further developing such engineering tools. In this review, we discuss established and emerging CRISPR-Cas-based tools for genome editing and transcription control of model and non model prokaryotes, and we analyse the possibilities for further improvement and expansion of these tools for next generation prokaryotic engineering.

引用

页码：575 / 587

页数：13

共 63 条

[1] Prokaryotic homologs of the eukaryotic DNA-end-binding protein Ku, novel domains in the Ku protein and prediction of a prokaryotic double-strand break repair system [J].

Aravind, L ;

Koonin, EV .

GENOME RESEARCH, 2001, 11 (08) :1365-1374

[2] CRISPR provides acquired resistance against viruses in prokaryotes [J].

Barrangou, Rodolphe ;

Fremaux, Christophe ;

Deveau, Helene ;

Richards, Melissa ;

Boyaval, Patrick ;

Moineau, Sylvain ;

Romero, Dennis A. ;

Horvath, Philippe .

SCIENCE, 2007, 315 (5819) :1709-1712

[3] Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials [J].

Bikard, David ;

Euler, Chad W. ;

Jiang, Wenyan ;

Nussenzweig, Philip M. ;

Goldberg, Gregory W. ;

Duportet, Xavier ;

Fischetti, Vincent A. ;

Marraffini, Luciano A. .

NATURE BIOTECHNOLOGY, 2014, 32 (11) :1146-1150

[4] Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system [J].

Bikard, David ;

Jiang, Wenyan ;

Samai, Poulami ;

Hochschild, Ann ;

Zhang, Feng ;

Marraffini, Luciano A. .

NUCLEIC ACIDS RESEARCH, 2013, 41 (15) :7429-7437

[5] Making ends meet: Repairing breaks in bacterial DNA by non-homologous end-joining [J].

Bowater, Richard ;

Doherty, Aidan J. .

PLOS GENETICS, 2006, 2 (02) :93-99

[6] Recombineering to homogeneity: extension of multiplex recombineering to large-scale genome editing [J].

Boyle, Nanette R. ;

Reynolds, T. Steele ;

Evans, Ron ;

Lynch, Michael ;

Gill, Ryan T. .

BIOTECHNOLOGY JOURNAL, 2013, 8 (05) :515-522

[7] Small CRISPR RNAs guide antiviral defense in prokaryotes [J].

Brouns, Stan J. J. ;

Jore, Matthijs M. ;

Lundgren, Magnus ;

Westra, Edze R. ;

Slijkhuis, Rik J. H. ;

Snijders, Ambrosius P. L. ;

Dickman, Mark J. ;

Makarova, Kira S. ;

Koonin, Eugene V. ;

van der Oost, John .

SCIENCE, 2008, 321 (5891) :960-964

[8] Gene silencing by CRISPR interference in mycobacteria [J].

Choudhary, Eira ;

Thakur, Preeti ;

Pareek, Madhu ;

Agarwal, Nisheeth .

NATURE COMMUNICATIONS, 2015, 6

[9] Classification and evolution of type II CRISPR-Cas systems [J].

Chylinski, Krzysztof ;

Makarova, Kira S. ;

Charpentier, Emmanuelle ;

Koonin, Eugene V. .

NUCLEIC ACIDS RESEARCH, 2014, 42 (10) :6091-6105

[10] Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases [J].

Citorik, Robert J. ;

Mimee, Mark ;

Lu, Timothy K. .

NATURE BIOTECHNOLOGY, 2014, 32 (11) :1141-1145

← 1 2 3 4 5 6 7 →