Preparation and comprehensive characterization of a calcium hydroxyapatite reference material

被引：386

作者：

Markovic, M ^{[1
]}

Fowler, BO

Tung, MS

机构：

[1] Natl Inst Stand & Technol, Amer Dent Assoc Hlth Fdn, Paffenbarger Res Ctr, Gaithersburg, MD 20899 USA

[2] Natl Inst Stand & Technol, Natl Inst Dent & Craniofacial Res,Mat Sci & Engn, NIH,Dent & Med Mat Grp,Polymers Div, Skeletal Dis Branch Res Associate Program, Gaithersburg, MD 20899 USA

来源：

JOURNAL OF RESEARCH OF THE NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY | 2004年 / 109卷 / 06期

关键词：

chemical analysis; crystal size; crystallinity; hydroxyapatite; infrared; morphology; preparation; Raman; solubility; surface area; thermal analysis; unit-cell parameters; x-ray diffraction;

D O I：

10.6028/jres.109.042

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

Numerous biological and chemical studies involve the use of calcium hydroxyapatite (HA), Ca-10(PO4)(6)(OH)(2). In this study detailed physicochemical characterization of HA, prepared from an aqueous solution, was carried out employing different methods and techniques: chemical and thermal analyses, x-ray diffraction, infrared and Raman spectroscopies, scanning and transmission microscopies, and Brunauer, Emmett, and Teller (BET) surface-area method. The contents of calcium (Ca2+), phosphate (PO43-), hydroxide (OH-), hydrogenphosphate (HPO42-), water (H2O), carbonate (CO32-), and trace constituents, the Ca/P molar ratio, crystal size and morphology, surface area, unit-cell parameters, crystallinity, and solubility of this HA were determined. This highly pure, homogeneous, and highly crystalline HA is certified as a National Institute of Standards and Technology (NIST) standard reference material, SRM 2910.

引用

页码：553 / 568

页数：16

共 38 条

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