Use of Convalescent Plasma Therapy in Two COVID-19 Patients With Acute Respiratory Distress Syndrome in Korea

被引：235

作者：

Ahn, Jin Young ^{[1
]}

Sohn, Yujin ^{[1
]}

Lee, Su Hwan ^{[1
]}

Cho, Yunsuk ^{[1
]}

Hyun, Jong Hoon ^{[1
]}

Baek, Yae Jee ^{[1
]}

Jeong, Su Jin ^{[1
]}

Kim, Jung Ho ^{[1
]}

Ku, Nam Su ^{[1
]}

Yeom, Joon-Sup ^{[1
]}

Roh, Juhye ^{[2
]}

Ahn, Mi Young ^{[3
]}

Chin, Bum Sik ^{[4
]}

Kim, Young Sam ^{[1
]}

Lee, Hyukmin ^{[2
]}

Yong, Dongeun ^{[2
]}

Kim, Hyun Ok ^{[2
]}

Kim, Sinyoung ^{[2
]}

Choi, Jun Yong ^{[1
]}

机构：

[1] Yonsei Univ, Coll Med, Severance Hosp, Dept Internal Med, Seoul, South Korea

[2] Yonsei Univ, Coll Med, Severance Hosp, Dept Lab Med, Seoul, South Korea

[3] Seoul Med Ctr, Dept Internal Med, Seoul, South Korea

[4] Natl Med Ctr, Dept Internal Med, Seoul, South Korea

来源：

JOURNAL OF KOREAN MEDICAL SCIENCE | 2020年 / 35卷 / 14期

关键词：

Coronavirus; SARS-CoV-2; COVID-19; Treatment; Convalescent Plasma; CORTICOSTEROID TREATMENT;

D O I：

10.3346/jkms.2020.35.e149

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 not yet has established its treatment, but convalescent plasma has been expected to increase survival rates as in the case with other emerging viral infections. We describe two cases of COVID-19 treated with convalescent plasma infusion. Both patients presented severe pneumonia with acute respiratory distress syndrome and showed a favorable outcome after the use of convalescent plasma in addition to systemic corticosteroid. To our knowledge, this is the first report of the use of convalescent plasma therapy for COVID-19 in Korea.

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