Estimation of regional lung expansion via 3D image registration

被引：5

作者：

Pan, Y ^{[1
]}

Kumar, D ^{[1
]}

Hoffman, EA ^{[1
]}

Christensen, GE ^{[1
]}

McLennan, G ^{[1
]}

Song, JH ^{[1
]}

Ross, A ^{[1
]}

Simon, BA ^{[1
]}

Reinhardt, JM ^{[1
]}

机构：

[1] Univ Iowa, Iowa City, IA 52242 USA

来源：

Medical Imaging 2005: Physiology, Function, and Structure From Medical Images, Pts 1 and 2 | 2005年 / 5746卷

关键词：

image registration; lung; biornechanics; X-ray CT;

D O I：

10.1117/12.596617

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A method is described to estimate regional lung expansion and related biomechanical parameters using multiple CT images of the lungs, acquired at different inflation levels. In this study, the lungs of two sheep were imaged utilizing a multi-detector row CT at different lung inflations in the prone and supine positions. Using the lung surfaces and the airway branch points for guidance, a 3D inverse consistent image registration procedure was used to match different lung volumes at each orientation. The registration was validated using a set of implanted metal markers. After registration, the Jacobian of the deformation field was computed to express regional expansion or contraction. The regional lung expansion at different pressures and different orientations are compared.

引用

页码：453 / 464

页数：12

共 20 条

[1] Measurement of regional lung function in rats using hyperpolarized 3helium dynamic MRI [J].