Synthesis of glycosylcurcuminoids

被引：49

作者：

Mohri, K

Watanabe, Y

Yoshida, Y

Satoh, M

Isobe, K

Sugimoto, N

Tsuda, Y

机构：

[1] Showa Pharmaceut Univ, Tokyo 1948543, Japan

[2] Natl Inst Hlth Sci, Setagaya Ku, Tokyo 1588501, Japan

[3] Univ Karachi, HEJ Res Inst Chem, Karachi 75270, Pakistan

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2003年 / 51卷 / 11期

关键词：

glycosylcurcuminoid; diglucosylcurcumin; monoglucosylcurcumin; digalactosylcurcumin; monogalactosylcurcumin;

D O I：

10.1248/cpb.51.1268

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Condensation of glycosylated arylaldehyde with acetylacetone-B2O3 Complex gave a corresponding diglycosylcurcuminoid, and a similar reaction using a mixture of arylaldehyde and glycosylarylaldehyde gave an unsymmetrical monoglycosylcurcuminoid, both as boron-complexes. The boron was removed from the complexes by heating in methanol, thus achieving the synthesis of di- and mono-glycosylcurcuminoids.

引用

页码：1268 / 1272

页数：5

共 18 条

[1] Hypolipidemic action of curcumin, the active principle of turmeric (Curcuma longa) in streptozotocin induced diabetic rats [J].