Ring closing metathesis as an efficient protocol for the stereoselective synthesis of spiro C-linked 4-deoxy disaccharides

被引：3

作者：

Reddy, Jakkidi J. ^{[1
]}

Begum, Asra ^{[1
]}

Jayaprakash, Pagadala ^{[1
]}

Sharma, Gangavaram V. M. ^{[1
]}

Kunwar, Ajit C. ^{[2
]}

机构：

[1] Indian Inst Chem Technol, Discovery Lab, Organ Chem Div 3, Hyderabad 500007, Andhra Pradesh, India

[2] Indian Inst Chem Technol, NMR Grp, Hyderabad 500007, Andhra Pradesh, India

来源：

LETTERS IN ORGANIC CHEMISTRY | 2008年 / 5卷 / 02期

关键词：

Grubbs catalyst; ring closing metathesis; stereoselective synthesis; spiro C-linked 4-deoxy disaccharides; bisallylic chirons;

D O I：

10.2174/157017808783743939

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ring closing metathesis protocol on bis-allylic chirons derived from sugars was utilized for the stereoselective synthesis of spiro C-linked deoxy disaccharides. Uloses derived from D-xylose and L-sorbose were converted into bis-allylic derivatives, which on RCM gave the spiro-pyrane rings. The xylose-derived spiro-pyrane on sequential oxidations was converted into new deoxy spiro C-disaccharides.

引用

页码：110 / 115

页数：6

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