Pregnancy in patients with myelodysplastic syndromes (MDS)

被引：11

作者：

Volpicelli, P. ^{[1
]}

Latagliata, R. ^{[1
]}

Breccia, M. ^{[1
]}

Carmosino, I. ^{[1
]}

Stefanizzi, C. ^{[1
]}

Napoleone, L. ^{[1
]}

Vozella, F. ^{[1
]}

Levi, A. ^{[1
]}

Natalino, E. ^{[1
]}

Alimena, G. ^{[1
]}

机构：

[1] Univ Roma La Sapienza, Dept Cellular Biotechnol & Hematol, I-00161 Rome, Italy

来源：

LEUKEMIA RESEARCH | 2008年 / 32卷 / 10期

关键词：

MDS; pregnancy; delivery;

D O I：

10.1016/j.leukres.2008.02.006

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We report 6 pregnancies in 5 females with low-risk myelodysplastic syndromes (MDS) (median age at diagnosis 28 years, range 26-29) observed in the last 15 years. In 2 cases pregnancy was concomitant to the diagnosis of MDS, in the remaining 4 cases the intervals from diagnosis were 2, 3,4 and 9 years, respectively. One patient had a foetal growth retardation corrected with steroid treatment while the remaining 5 pregnancies were uneventful. After a median time from delivery of 104 months (range 18-187) none of the patients developed acute myeloid leukemia (AML) and all are alive in stable disease. In conclusion, selected females with low-risk MDS could not be discouraged to have full term pregnancies. (c) 2008 Elsevier Ltd. All rights reserved.

引用

页码：1605 / 1607

页数：3

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