Social deficits in male children and adolescents with sex chromosome aneuploidy: A comparison of XXY, XYY, and XXYY syndromes

被引：68

作者：

Cordeiro, Lisa ^{[2
]}

Tartaglia, Nicole ^{[1
,2
]}

Roeltgen, David ^{[3
]}

Ross, Judith ^{[3
]}

机构：

[1] Childrens Hosp Colorado, Child Dev Unit, Aurora, CO 80045 USA

[2] Univ Colorado, Sch Med, Dept Pediat, Aurora, CO 80045 USA

[3] Thomas Jefferson Univ, Dept Pediat, Philadelphia, PA 19107 USA

来源：

RESEARCH IN DEVELOPMENTAL DISABILITIES | 2012年 / 33卷 / 04期

关键词：

Klinefelter syndrome (KS); Autism; Social deficits; Social skills; XXY; XYY; XXYY; KLINEFELTER SYNDROME; AUTISM; BOYS; 47; XXY; GENES; DISORDER; MUTATION; 48; XXYY; INFANTS; TRAITS;

D O I：

10.1016/j.ridd.2012.02.013

中图分类号：

G76 [特殊教育];

学科分类号：

040109 ;

摘要：

We compare social skills in three groups of males with sex chromosome aneuploidies (SCAs) using the Social Responsiveness Scale (SRS). Participants included males with XXY (N = 102,M = 10.08 years), XYY (N = 40, M = 9.93 years), and XXYY (N = 32, M = 11.57 years). XXY had lower (better) SRS scores compared to XYY and XXYY. Scores were not significantly different between XYY and XXYY. In all groups, there were significantly more with SRS scores in the severe range compared to the SRS normative sample. All groups scored lowest (better) on Social Motivation. Relationships between SRS scores and demographic and clinical variables were examined. Results describe the social skills in males with SCA, and suggest that an additional Y chromosome may contribute to increased risk of autistic behaviors. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：1254 / 1263

页数：10

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